review2021· PLOS One
Efficacy and safety of Ashwagandha root extract in stress and anxiety: a systematic review
Cheah KL, Norhayati MN, Husniati Yaacob L, et al.
AshwagandhaSystematic review of clinical trials suggesting Ashwagandha extract reduces stress and anxiety with good tolerability.
Key findings
Significant reduction in serum cortisol and self-reported anxiety across multiple trials.
clinical trial2014· Clin Interv Aging
Randomized placebo-controlled trial of Curcumin in knee osteoarthritis
Kuptniratsaikul V, et al.
TurmericCurcumin extract showed comparable efficacy to ibuprofen in knee osteoarthritis pain with fewer adverse events.
Key findings
Pain and function improvements equivalent to NSAID comparator; better safety profile.
clinical trial2001· Psychopharmacology
Bacopa monnieri improves memory and attention: a double-blind placebo-controlled trial
Stough C, et al.
BrahmiStandardized Brahmi extract improved verbal learning, memory consolidation and attention over 12 weeks.
Key findings
Significant improvement in cognitive measures with no serious adverse effects.
pharmacological2014· J Ayurveda Integr Med
Phytochemistry and pharmacology of Ocimum sanctum: a review
Cohen MM
TulsiComprehensive review of Tulsi's chemical constituents and immunomodulatory, adaptogenic activity.
Key findings
Eugenol and ursolic acid drive reproducible anti-stress and antimicrobial effects.
pharmacological2016· Evid Based Complement Alternat Med
Antibacterial and antifungal activity of Azadirachta indica (Neem) leaf extract
Alzohairy MA
NeemIn vitro confirmation of broad-spectrum antimicrobial activity of neem leaf extracts.
Key findings
Effective against multiple bacterial and fungal strains; supports traditional skin use.
ethnobotanical~300 BCE· Classical Ayurvedic text
Charaka Samhita — Medhya Rasayana chapter (classical reference)
Acharya Charaka
BrahmiEarliest systematic classification of Medhya (cognition-enhancing) Rasayanas including Brahmi.
Key findings
Brahmi classified foremost among Medhya Rasayanas for memory and intellect.